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随着对间质纤维化的细胞和生化机制的了解，新的治疗措施应针对防止间质纤维化的发生。Ｐｉｒｆｅｎｉｄｏｎｅ具有抗转化生长因子－β（ＴＧＦ－β）的作用。肾、肺间质纤维化的临床和实验研究证实它能阻止甚至逆转间质纤维化的发生
With the understanding of the cellular and biochemical mechanisms of interstitial fibrosis, new therapies should address the prevention of interstitial fibrosis. Pirfenidone has anti-transforming growth factor-β (TGF-β) effects. Clinical and experimental studies of renal and pulmonary interstitial fibrosis confirm that it prevents or even reverses the occurrence of interstitial fibrosis