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作者对54例主动脉瓣狭窄(主窄)病人进行一条列心导管检查,旨在研究其血液动力学的演进规律。其中男47例,女7例,平均年龄61.2岁。观察研究时间平均为4.4(0.4～12.2)年,37例(69％)伴冠脉疾病,按 Hakkis 公式计算主动脉瓣口面积,最初平均面积为1.26(0.66～2.85)cm~2,最后随访时为.77(0.29～1.95)cm~2,平均缩小0.49cm~2。平均收缩期左室与主动脉峰值压力阶差(压差)从最初时23.3±15.1增至最后随访时为52.6±27.5mmHg,平均增加29.3±23.6mmHg,两者具有显著性差异(P<0.001)。作者对38例有症状发展的病人进行第二次心导管检查,结果提示这些病人均有病变的发展。作者认为,虽然对症状轻微的病人作一系列心导管检查,并进行前瞻性对照研究会取得满意的效果,但实际上要
The author of a series of 54 patients with aortic stenosis (main narrow) column catheter examination, designed to study the evolution of hemodynamics. There were 47 males and 7 females, with an average age of 61.2 years. The mean duration of observation and study was 4.4 (0.4-12.2) years and 37 (69%) were coronary artery disease. The aortic valve area was calculated according to the Hakkis formula with an initial mean area of 1.26 (0.66-2.85) cm ~ 2 and the final follow-up (0.29 ~ 1.95) cm ~ 2, the average reduction of 0.49cm ~ 2. Mean systolic left ventricular and aortic peak pressure gradient (pressure) increased from the initial 23.3 ± 15.1 to the final follow-up 52.6 ± 27.5mmHg, an average increase of 29.3 ± 23.6mmHg, both significant differences (P <0.001 ). The authors performed a second cardiac catheterization of 38 patients with symptomatic development, suggesting that these patients had pathological changes. The authors believe that although a series of cardiac catheterization tests for patients with mild symptoms and prospective controlled studies will achieve satisfactory results,