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目的分析一起接种卡介苗和乙肝疫苗后偶合巨大血管瘤伴血小板减少综合征病例,为开展疑似预防接种异常反应(AEFI)监测提供参考。方法用描述性方法分析个案调查诊断资料。结果一出生20d的男婴在同时接种卡介苗和乙肝疫苗后13d,出现右颈面部红肿包块伴血小板减少,经2次转院治愈。诊断:新生儿巨型血管瘤并血小板减少。接种门诊报告AEFI。崇阳县预防接种异常反应调查诊断专家组,根据患儿发病经过、病情进展及临床诊治综合分析,判定可能是新生儿血管瘤导致血小板减少,与预防接种无因果关系,属于预防接种偶合症。结论实施疫苗接种工作中,应加强对血管瘤-血小板减少综合征的临床诊治培训,提高对本病的认识及AEFI的监测处置能力。
Objective To analyze the cases of coupled giant hemangioma with thrombocytopenia after BCG vaccination and hepatitis B vaccination, and provide a reference for the surveillance of abnormal immunization with suspected vaccination. Methods Descriptive methods were used to analyze case-finding diagnostic data. Results A 20-day-old male baby presented with swollen and right-sided mass with thrombocytopenia 13 days after BCG and hepatitis B vaccination. Diagnosis: Neonatal giant hemangioma with thrombocytopenia. Inoculation clinic report. Chongyang County vaccination anomalous response diagnosis expert group, according to children with the onset of disease, disease progression and clinical diagnosis and treatment of a comprehensive analysis of the decision may be neonatal hemangioma lead to thrombocytopenia, and vaccination without causal relationship, are vaccination coupled disease. Conclusion In the course of vaccination, we should strengthen the training of clinical diagnosis and treatment of hemangioma - thrombocytopenic syndrome and improve the understanding of this disease and the monitoring and disposal capacity of AEFI.