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目的 对绝经后女性 2型糖尿病患者血清性激素水平变化与脑梗死并发症关系进行探讨。方法 测定 2 5例绝经后女性 2型糖尿病合并脑梗死 (A组 ) ;2 7例 2型糖尿病未合并脑梗死 (B组 ) ;2 1例绝经后正常女性 (C组 )的血清雌二醇 (E2 )、孕激素 (P)、促卵泡刺激素 (FSH)、促黄体生成素 (LH)和孕酮 (T)水平。结果 绝经后女性2型糖尿病并发脑梗死者血清E2 较正常绝经后女性显著降低 ,FSH、LH、T显著提高。结论 绝经后女性性激素水平变化与 2型糖尿病脑梗死并发症有关。
Objective To investigate the relationship between serum sex hormone levels and cerebral infarction complications in postmenopausal women with type 2 diabetes mellitus. Methods A total of 25 postmenopausal women with type 2 diabetes mellitus complicated with cerebral infarction (group A) were enrolled in this study. Twenty-seven patients with type 2 diabetes without cerebral infarction (group B) and 21 postmenopausal women (group C) with serum estradiol (E2), progesterone (P), follicle stimulating hormone (FSH), luteinizing hormone (LH) and progesterone (T). Results Serum E2 in postmenopausal women with type 2 diabetes mellitus complicated with cerebral infarction was significantly lower than that in normal postmenopausal women, and FSH, LH and T were significantly increased. Conclusions The changes of sex hormone levels in postmenopausal women are related to the complication of type 2 diabetes mellitus.