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目的:探讨中央性前置胎盘发生的高危因素及其对妊娠结局的影响。方法:对我院283例中央性前置胎盘患者和126例正常剖宫产孕产妇进行病例对照研究。结果:病例组孕产妇的人工流产史、自然分娩史高于对照组(P<0.05),而病例组孕周、产检次数低于对照组(P<0.05)。病例组产后出血、胎盘粘连、胎盘植入、贫血等妊娠结局发生率均高于对照组(P<0.05),而胎心和出生体重低于对照组(P<0.05)。非条件Logistic回归分析表明,产检次数(OR=0.586,95%CI:0.515~0.666)是中央性前置胎盘的保护因素,人工流产(OR=1.843,95%CI:1.152~2.947)是危险因素。结论:中央性前置胎盘能增加不良妊娠结局的发生率;产检次数可以降低中央性前置胎盘发生风险,人工流产能增加其发生风险。
Objective: To investigate the risk factors of central placenta previa and its effect on pregnancy outcome. Methods: A case-control study was performed on 283 cases of central placenta previa and 126 cases of normal cesarean section in our hospital. Results: The history of induced abortion and spontaneous labor of pregnant women in case group were higher than those in control group (P <0.05). The gestational weeks and the number of births in case group were lower than those in control group (P <0.05). The incidence of postpartum hemorrhage, placental adhesion, placenta accreta and anemia were higher in the case group than in the control group (P <0.05), while the fetal heart rate and birth weight were lower than those in the control group (P <0.05). Non-conditional Logistic regression analysis showed that the number of births (OR = 0.586,95% CI: 0.515-0.666) was a protective factor in central placenta previa. Induced abortion (OR = 1.843, 95% CI: 1.152-2.947) was a risk factor . Conclusion: The central placenta previa can increase the incidence of adverse pregnancy outcomes; the number of examinations can reduce the risk of central placenta previa, abortion can increase its risk.