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目的探讨青岛市成人麻疹发病的相关因素。方法采用病例对照研究的方法,收集青岛市2002-2003年发生的全部成人麻疹病例70例和140名健康对照人群的一般社会人口经济学因素、麻疹疫苗免疫史、人口性质等信息。结果单因素及多因素分析结果显示:病例组中无麻疹疫苗免疫史的比例明显高于对照组(χ2=26.88,P<0.05,OR=5.12,95%CI:2.69~9.73),按照接受免疫的次数,分为0次、1次、≥2次3个等级进行比较分析,0次麻疹疫苗免疫史与1次免疫史比较,两组的差异无统计学意义(χ2=1.86,P=0.173);0次麻疹疫苗免疫史与≥2次免疫史进行比较显示,两组间的差异有统计学意义(χ2=45.24,P=0.000,OR=13.35,95%CI:5.80~30.71);有1次麻疹疫苗免疫史与≥2次免疫史在两组中的分布差异也有统计学意义(χ2=26.23,P=0.000,OR=7.91,95%CI:3.37~18.59)。外来人口的麻疹发病比例明显高于本地人(χ2=21.60,P<0.01,OR=4.06,95%CI:2.21~7.45);单因素分析提示,两组人群经济收入水平差异有统计学意义(χ2=2.23,P<0.05,OR=2.08,95%CI:1.15~3.76)。结论无麻疹疫苗免疫史人群、外来人口、低经济收入人群是青岛市成人麻疹发病的高危人群。
Objective To explore the related factors of adult measles in Qingdao. Methods A case-control study was conducted to collect information on the general socio-economic factors, the immunization history of measles vaccine, and the nature of the population in 70 adult cases of measles and adult controls from 2002 to 2003 in Qingdao. Results The results of univariate and multivariate analysis showed that the proportion of cases without measles vaccine immunization history was significantly higher than that of the control group (χ2 = 26.88, P <0.05, OR = 5.12, 95% CI: 2.69-9.73) (Χ2 = 1.86, P = 0.173), there was no significant difference between the two groups (0 2 times, 1 times, ≥2 times). There was no significant difference between the two groups ); 0 times the history of measles vaccine immunization and ≥ 2 immunization history showed that the difference between the two groups was statistically significant (χ2 = 45.24, P = 0.000, OR = 13.35,95% CI: 5.80 ~ 30.71) There was also a statistically significant difference in the immunization history of one measles vaccine and ≥2 immunizations in the two groups (χ2 = 26.23, P = 0.000, OR = 7.91, 95% CI: 3.37-18.59). The incidence of measles in the migrant population was significantly higher than that of the locality (χ2 = 21.60, P <0.01, OR = 4.06, 95% CI: 2.21-7.45). Univariate analysis indicated that the income level of the two groups was statistically different χ2 = 2.23, P <0.05, OR = 2.08, 95% CI: 1.15-3.76). Conclusion No measles vaccine history of immunization, migrants, low-income people in Qingdao City, the incidence of adult measles high-risk groups.