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目的 :比较预防性使用单剂或 4剂头孢曲松 (Cef)对肺、食管外科手术的预防感染效益。方法 :前瞻性随机对照研究 ,30 3例病人随机分配到单剂组 (n=15 1)或 4剂组 (n=15 2 )。结果 :单剂组和 4剂组术后感染率分别为 5 .3%和 7.2 % (P>0 .0 5 ) ;两组住院时间也无显著性差异。结论 :单剂 Cef是肺、食管手术经济、有效的预防性方案。
Objectives: To compare the prophylactic efficacy of prophylactic use of Cef against prophylactic infections of lung and esophageal surgery. METHODS: In a prospective randomized controlled study, 30 3 patients were randomized to single-dose (n = 15 1) or 4 doses (n = 15 2). Results: The postoperative infection rates of single dose and four dose groups were 5.3% and 7.2%, respectively (P> 0.05). There was no significant difference in length of stay between the two groups. Conclusions: Single-dose Cef is an economical and effective prophylactic regimen for pulmonary and esophageal surgery.