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目的:观察针刺结合纳洛酮治疗重度急性酒精中毒临床疗效。方法:将80例重度急性酒精中毒患者随机分为2组各40例。对照组予常规基础治疗加用纳洛酮治疗;治疗组在对照组治疗方案的基础上加针刺治疗。观察2组患者格拉斯哥昏迷评分(GCS),比较2组清醒时间、清醒后主诉症状情况以及纳洛酮人均使用量。结果:治疗后,2组GCS评分分别与治疗前比较,差异均有统计学意义(P<0.01);治疗组GCS评分高于对照组,差异有统计学意义(P<0.01);治疗组清醒时间短于对照组,差异有统计学意义(P<0.01);2组患者清醒后,对照组主诉症状较治疗组多,临床不舒适率高于治疗组,差异均有统计学意义(P<0.01);治疗后,治疗组纳洛酮人均用量低于对照组,差异有统计学意义(P<0.01)。结论:针刺结合纳洛酮治疗重度急性酒精中毒疗效良好,能减少解酒药物药量的使用,较为快速醒酒,改善患者酒精中毒症状,提高患者的临床舒适度。
Objective: To observe the clinical effect of acupuncture combined with naloxone in the treatment of severe acute alcoholism. Methods: 80 patients with severe acute alcoholism were randomly divided into two groups of 40 cases. The control group was given routine basic treatment plus naloxone treatment; the treatment group in the control group based on the treatment program plus acupuncture treatment. The Glasgow Coma Scale (GCS) was observed in two groups. The awake time of the two groups, the symptoms of symptoms after awake and the per capita consumption of naloxone were compared. Results: After treatment, the GCS scores of the two groups were significantly different from those before treatment (P <0.01); GCS score of the treatment group was higher than that of the control group (P <0.01) Time was shorter than the control group, the difference was statistically significant (P <0.01). After the two groups of patients awake, the symptoms in the control group were more than those in the treatment group, and the clinical discomfort rate was higher than that in the treatment group (P < 0.01). After treatment, the average dosage of naloxone in the treatment group was lower than that in the control group (P <0.01). Conclusion: Acupuncture combined with naloxone in the treatment of severe acute alcoholism has a good curative effect, which can reduce the use of anti-alcohol drugs, quicker sober up, improve symptoms of alcoholism and improve patient’s clinical comfort.