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目的:探讨1 470nm半导体激光经尿道前列腺汽化术治疗BPH的疗效和安全性。方法:应用1470nm半导体激光对46例BPH患者进行激光汽化切除术。患者年龄62~86岁,平均前列腺体积为(56.2±12.1)ml。同时观察记录手术时间、术中出血量、手术并发症及手术前后IPSS、生活质量评分(QOL)、最大尿流率(Qmax)及剩余尿量(PVR)等指标,评估其差异有无统计学意义。结果:本组手术全部成功,手术时间平均(75.6±14.8)min,术中无明显出血,无输血病例。术后导尿管留置时间2~4d,平均留置尿管时间(2.5±0.4)d;IPSS术后1个月为(8.8±2.2)分,3个月为(7.6±1.2)分,明显低于术前[(18.5±3.6)分,P<0.01],Qmax及PVR明显好于术前(P<0.01)。所有患者均未出现尿失禁及明显的膀胱刺激症状。结论:1 470nm半导体激光汽化术治疗BPH效果肯定,值得临床推广。
Objective: To investigate the efficacy and safety of 1470nm laser transurethral vaporization of the prostate in the treatment of BPH. Methods: 46 cases of BPH patients underwent laser vaporization with 1470nm semiconductor laser. Patients aged 62 to 86 years, the average prostate volume was (56.2 ± 12.1) ml. At the same time, the indexes such as operation time, intraoperative blood loss, operation complications and IPSS, QOL, Qmax and residual urine volume (PVR) were recorded to evaluate whether there was statistical difference significance. Results: All the operations were successful in this group. The average operation time was (75.6 ± 14.8) min. There was no obvious hemorrhage and no blood transfusion in operation. Postoperative urinary catheter placement time was 2 ~ 4 days, mean catheterization catheterization time was (2.5 ± 0.4) days; IPSS was (8.8 ± 2.2) in 1 month and was (7.6 ± 1.2) in 3 months, Preoperative [(18.5 ± 3.6) min, P <0.01], Qmax and PVR were significantly better than preoperative (P <0.01). All patients did not have urinary incontinence and obvious symptoms of bladder irritation. Conclusion: 1 470nm laser diode laser treatment of BPH affirmed, worthy of clinical promotion.