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自从Lim和Sun于1980年提出生物微胶囊概念以来[1],微胶囊技术在生物医学领域被广泛应用。细胞在微胶囊内呈三维立体多细胞聚集生长,这种聚集生长具有贴壁细胞无法比拟的优点,更接近在体细胞、组织的特性[2]。细胞骨架与细胞运动、细胞形态和跨膜信息传递等功能密切相关[3]。对
Since Lim and Sun proposed the concept of biological microcapsules in 1980 [1], microcapsule technology has been widely applied in the field of biomedicine. Cells in the microcapsules were three-dimensional three-dimensional multicellular accumulation of growth, such an accumulation of adherent cells with unparalleled advantages, closer to the somatic cells, tissue characteristics [2]. Cytoskeleton and cell movement, cell morphology and transmembrane information delivery and other functions are closely related [3]. Correct