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目的观察复方夏天无片治疗轻度癌痛的疗效。方法将76例符合入组标准的轻度癌痛病患者随机分成两组各38例。治疗组用复方夏天无片口服,每日3次,每次2片,连续使用2周。对照组用非甾体抗炎药双氯酚酸钠肠溶片,每日3次,每次50 mg,方法及疗程均与治疗组相同。结果治疗组总有效率89.5%,对照组的总有效率88.2%,两组比较无显著性差异(P>0.05);治疗组不良反应发生率仅为7.89%,且症状比较轻微;而对照组双氯酚酸钠不良反应发生率为23.68%,尤其是胃肠反应及肝、肾功能损害比较突出,症状也比较明显,患者耐受性较差,经统计分析有极显著差异(P<0.01)。结论复方夏天无片治疗轻度癌痛与双氯酚酸钠肠溶片效果相似,但不良反应发生率少。
Objective To observe the curative effect of compound summer tablet-free treatment of mild cancer pain. Methods A total of 76 patients with mild cancer pain who met the inclusion criteria were randomly divided into two groups of 38 patients. The treatment group with compound summer no tablet orally, 3 times a day, each 2 tablets, continuous use for 2 weeks. The control group with non-steroidal anti-inflammatory drugs diclofenac sodium enteric-coated tablets, 3 times a day, each 50 mg, methods and treatment are the same with the treatment group. Results The total effective rate was 89.5% in the treatment group and 88.2% in the control group, with no significant difference between the two groups (P> 0.05). The incidence of adverse reactions in the treatment group was only 7.89%, and the symptoms were mild. In the control group Diclofenac sodium adverse reaction rate was 23.68%, especially gastrointestinal reactions and liver and kidney dysfunction more prominent symptoms are more obvious, the patient tolerance is poor, statistically significant (P <0.01 ). Conclusions The summer painless treatment of mild cancer pain with diclofenac sodium enteric-coated tablets is similar, but the incidence of adverse reactions less.