应用免疫细胞化学,我们曾研究针刺对大鼠脊髓内P物质甲硫氨酸脑啡肽的作用·由于这些肽类牵涉到脊髓痛的传导过程,亦即:P物质可在感受伤害中起作用及与鸦片受体立体持异性结合的脑啡肽具有镇痛的作用。我们应用大鼠研究的资料表明:针刺就像应用吗啡那样,可使脊髓后角胶状质神经元内的P物质增加,而针刺后甲硫氨酸脑啡肽根据抗血清的不同而出现不同程度的降低,我们把我们的资料理解为:针刺可使鸦片样肽、脑啡肽释放、也可通过邻近的突起阻滞P物质的释放,根据现行脊髓痛觉传导过程的假说,脑啡肽神经元可 Using immunocytochemistry, we have studied the effect of acupuncture on the substance P, methionine, enkephalin, in the spinal cord of rats. Since these peptides involve the process of spinal cord pain conduction, that is, substance P can play The enkephalin, which plays a role of stereospecifically binding with opioid receptor, has analgesic effect. Our data from rat studies indicate that acupuncture, like morphine, increases substance P in the dorsal horn neurons of the spinal cord, whereas methionine enkephalin after acupuncture varies depending on antisera We may interpret our data as follows: acupuncture can release the opioid peptide and enkephalin, and block the release of substance P through the adjacent protuberances. According to the hypothesis of the current process of spinal pain conduction, the brain Neuropeptide neurons can be