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作者报告一例无免疫缺陷证据的患者发生脑肉芽肿性血管炎,引起广泛的脑梗死,并从脑组织和脑脊液中分离出人嗜T 淋巴细胞Ⅲ型病毒(HTLV-Ⅲ)。患者男性,42岁,同性恋者。入院前一月发现精神状态异常表现为易激动和阵发性意识模糊,尚伴有经常性双额疼痛。体温39℃,体检及神经系统检查正常。CSF:WBC329/mm~3其中淋巴细胞占97%,单核细胞占3%,糖85mg/dl 蛋白123mg/dl。细菌培养、梅毒血清学试验(VDRL)阴性,常规给予青霉素治疗。因持续高烧,精神状态进行性恶化而于第6天转院。此时检查生命体征正常,对名称有反应,但对地点和时间定向差。能向前重复六位数字,但不能后数,知道自己的生日和住址,但
The authors report a case of brain granulomatous vasculitis in a patient without evidence of immune deficiency, causing extensive cerebral infarction and isolating human T-Lymphocytic Virus III (HTLV-III) from brain tissue and cerebrospinal fluid. Male patient, 42 years old, same-sex person. One month prior to admission, abnormal mental status was found to be agitated and paroxysmal, accompanied by recurrent bilateral pain. Body temperature 39 ℃, physical examination and normal nervous system examination. CSF: WBC329 / mm ~ 3 of which lymphocytes accounted for 97%, monocytes accounted for 3%, 85mg / dl protein 123mg / dl. Bacterial culture, syphilis serological test (VDRL) negative routine penicillin treatment. On the 6th day due to persistent high fever, progressive mental deterioration. At this point check the normal vital signs, the name of the reaction, but the location and time-oriented poor. Can repeat the six numbers forward, but can not after the number, know their birthday and address, but