论文部分内容阅读
目的研究钟乳石的炮制机制。方法通过钟乳石炮制前后含量测定、热分析法研究、扫描电镜观察、FT-IR光谱分析、X-衍射Fourier图谱分析、微量元素分析及化学元素入血的比较研究,来探讨钟乳石的炮制机制。结果钟乳石经过炮制后,钙含量明显增加;钟乳石的主要化学成分碳酸钙部分分解成氧化钙;物质的物相、晶质发生了较大变化,而不单纯是成分的改变;钟乳石所含元素的数目和比例均发生了改变,均符合国家药典中的限量规定;与钟乳石生品相比,炮制后的钟乳石经灌胃后,血钾、血钠含量均有所降低,并在大鼠血清中检出了元素Sn。结论钟乳石炮制后质变疏松,易于粉碎和煎出有效成分,并且炮制有减毒、增效的作用,表明钟乳石的炮制有一定意义。
Objective To study the processing mechanism of stalactites. Methods The stomatal mechanism of stalactite was studied by content determination, thermal analysis, scanning electron microscope observation, FT-IR spectrum analysis, X-ray diffraction pattern analysis, trace element analysis and comparison of chemical elements in blood before and after processed by stalactite. Results After the stalactites were processed, the content of calcium increased obviously. The calcium carbonate, the main chemical component of stalactites, was partially decomposed into calcium oxide. The phase and crystal quality of the material changed greatly, not simply the change of composition. The numbers and proportions of the stalactites changed, all of them were in accordance with the limits of the national pharmacopoeia. Compared with stalactite products, the processed stalactites were reduced in serum potassium and serum sodium after gavage, and in the serum of rats The element Sn was detected. Conclusion The stalactites were loose after processing, easily crushed and fried out the active ingredients, and the processing of the stalactites had the effect of attenuation and synergism, indicating that the stalactites processing has some significance.