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本文观察了３２例非何杰金淋巴瘤（ＮＨＬ）患者红细胞铜锌超氧化物歧化酶（ＲＢＣ·Ｃｕ·Ｚｎ·ＳＯＤ），血清脂质过氧化物（ＬＰＯ）和维生素Ｅ（ＶＥ）值的变化，结果表明ＮＨＬ患者ＲＢＣ·Ｃｕ·Ｚｎ·ＳＯＤ活力和ＶＥ水平明显降低（Ｐ＜０．０５及Ｐ＜０．０１），ＬＰＯ值明显增高（Ｐ＜０．０１）。对其中１３例患者进行动态观察，除合并白血病的２树治疗无效外，其余１１例治疗后均获缓解，其ＲＢＣ·Ｃｕ·Ｚｎ·ＳＯＤ活力、血清ＬＰＯ、ＶＥ浓度均在半年内基本恢复正常。反映了ＮＨＬ患者体内过氧反应增强及对组织的损伤，氧自由基（ＯＦＲ）产生和清除平衡的破坏，而治疗后对ＯＦＲ所致的机体损伤可望得到部分恢复。
In this paper, we observed the changes of erythrocyte copper, zinc, superoxide dismutase (RBC · Cu · Zn · SOD), serum lipid peroxide (LPO) and vitamin E (VE) in 32 patients with non-Hodgkin’s lymphoma (NHL) (P <0.05 and P <0.01), and the LPO value was significantly increased (P <0.01) in patients with NHL. The results showed that the activity of RBC · Cu · Zn · SOD and the level of VE were significantly decreased in NHL patients. Thirteen of the patients were observed dynamically. All the 11 patients except leptin-2 treated with leukemia were relieved. The activity of RBC · Cu · Zn · SOD and LPO and VE in serum returned to normal within six months . Reflects the NHL patients with increased peroxidation and tissue damage in vivo, the generation of oxygen free radicals (OFR) and the destruction of the balance of damage, and treatment of OFR-induced damage to the body is expected to be partially restored.