Western China includes 12 provincial divisions (the 7 provinces of Sichuan, Guizhou, Yunnan, Shaanxi, Gansu, Qinghai and; 5 autonomous regions of Tibet, Ningxia, Xinjiang, Inner Mongolia and Guangxi; and one city of Chongqing), which comprise 71.4% of the national land area, 28.5% of the national population and produce 17.5% of the national GDP in China. There are 17 countries that have riparian relationships with western China, most of which are water-short countries. All are listed by UN ESCAP as countries with potential water crisis. The co-operative development and coordinated management of international rivers in western China is an important step toward the implementation of the national Great Western Development program. Taking into account of the national strategy and object hierarchy, as well as the development demand of the western region, it is necessary to pursue the multi-disciplinary study of the equitable allocation, utilisation, and eco-environment protection of transboundary water resources in the region. Such efforts will undoubtedly provide scientific evidence and support for the decision-making of the environmental protection and ecological construction and management in the western regions, the enforcement of the sub-regional economic co-operation, mitigation of trans-boundary conflicts, and enhancing bio-diversity conservation. China includes 12 provincial divisions (the 7 provinces of Sichuan, Guizhou, Yunnan, Shaanxi, Gansu, Qinghai and; 5 autonomous regions of Tibet, Ningxia, Xinjiang, Inner Mongolia and Guangxi; and one city of Chongqing), which comprise 71.4% of the national land area, 28.5% of the national population and produce 17.5% of the national GDP in China. There are 17 countries that have riparian relationships with western China, most of which are water-short countries. All are listed by UN ESCAP as countries with potential water crisis. The co-operative development and coordinated management of international rivers in western China is an important step toward the implementation of the national Great Western Development program. Taking into account of the national strategy and object hierarchy, as well as the development demand of the western region, it is necessary to pursue the multi-disciplinary study of the equitable allocation, utilisation, and eco-environment protection of transbo unduly water resources in the region. Such efforts will undoubtedly provide scientific evidence and support for the decision-making of the environmental protection and ecological construction and management in the western regions, the enforcement of the sub-regional economic co-operation, mitigation of trans -boundary conflicts, and enhancing bio-diversity conservation.