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目的探讨基层医院代谢综合征在不稳定型心绞痛患者人群中的发病情况并分析其对预后的影响。方法筛选初发不稳定型心绞痛入院的患者189例,进行为期两年的随访。将患者分为合并代谢综合征组(96例)和无代谢综合征组(93例)。平均随访时间(24.3±14.6)个月。比较两组患者的主要心脏事件发生情况和病死率,分析代谢综合征对不稳定型心绞痛患者预后的影响。结果不稳定型心绞痛患者中代谢综合征的患病率为50.8%;合并代谢综合征组患者较无代谢综合征组患者远期出现了更多的复发心绞痛(21.8%vs10.7%,P=0.006),及再住院增加(P=0.006),但两组在心肌梗死、心源性死亡等方面,差异无统计学意义(P>0.05);合并代谢综合征组不稳定型心绞痛患者病死率为23.9%。结论基层医院中代谢综合征在不稳定型心绞痛患者中具有较高的患病率和病死率,是预测不稳定型心绞痛患者预后的危险因素。
Objective To investigate the incidence of metabolic syndrome in primary hospital patients in patients with unstable angina and to analyze its impact on prognosis. Methods A total of 189 hospitalized patients with newly diagnosed unstable angina pectoris were enrolled and were followed up for two years. The patients were divided into metabolic syndrome group (96 cases) and no metabolic syndrome group (93 cases). The average follow-up time (24.3 ± 14.6) months. The incidence of major cardiac events and mortality were compared between the two groups, and the effect of metabolic syndrome on the prognosis of patients with unstable angina pectoris was analyzed. Results The prevalence of metabolic syndrome in patients with unstable angina was 50.8%. Patients with metabolic syndrome had longer-term recurrence of angina (21.8% vs 10.7%, P = 0.006), and increased rehospitalization (P = 0.006). However, there was no significant difference between the two groups in terms of myocardial infarction and cardiac death (P> 0.05). The mortality of patients with unstable angina pectoris in the metabolic syndrome group 23.9%. Conclusions Metabolic syndrome in primary hospitals has a high prevalence and mortality in patients with unstable angina and is a risk factor for predicting the prognosis of patients with unstable angina.