论文部分内容阅读
鉴于甲状腺对碘有选择性吸收性能,因而在1941年Hertz及Roberts两氏首先应用放射性碘~(130)及碘~(131)的混合剂,治疗10名甲状腺毒症患者,其中碘~(131)約占起始剂量的90％。在同年Hamilton及Lawrence两氏在免和狗中应用了大剂量的碘~(131),所有动物的甲状腺差不多完全被破坏,其他組織和器官并未发現变化;以后他們就用碘~(131)治疗3名甲状腺机能亢进患者,引起了許多学者的兴趣。由于甲状腺具有选择性吸收碘的能力,所以蓄积在甲状腺中的碘量数千倍于血中的含量,因此放射能的破坏作用仅局限于甲状腺增生过盛的組織,加以碘~(131)的放射性有99％是β射线,故其破坏作用仅表现在2毫米的距离以內(碘~(131)β射线在组
Given the selective absorption of iodine by the thyroid, Hertz and Roberts first treated 10 patients with thyrotoxicosis in 1941 with iodine ~ (131) and iodine ~ (131) ) Accounts for about 90% of the initial dose. In the same year, both Hamilton and Lawrence applied large doses of iodine 131 to the dogs and dogs. All animals had almost complete destruction of the thyroid gland and no changes in other tissues and organs. Afterwards, they used iodine 131 ) Treatment of three patients with hyperthyroidism, has aroused the interest of many scholars. Since thyroid has the ability to selectively absorb iodine, the amount of iodine accumulated in the thyroid is thousands of times higher than that in blood. Therefore, the destructive effect of radiation is confined to the tissue where thyroid hyperplasia is excessive, and iodine (131) 99% of radioactivity is beta radiation, so its destructive effect is only reflected in the distance of 2 mm (iodine ~ (131) beta rays in the group