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目的:观察他克莫司对特发性膜性肾病的治疗效果。方法:对在我院进行治疗的50例患者的临床资料进行回顾性分析,在对患者临床特征密切观测的同时,分出实验组和对照组,实验组使用他克莫司治疗,对照组采用环磷酰胺等其他药物治疗,进行分析比较,观察各组的疗效。结果:实验组和对照组的有效率分别是93.75%和77.78%,采用他克莫司的治疗效果有很少的副作用,并且在停药以后不容易复发。结论:在特发性膜性肾病患者身上,利用他克莫司的治疗效果比较好,可以很明显地缓解病情,不良反应症状少,在治疗过程中,必须根据不同患者的不同体质特征进行正确诊断,对症下药,才能达到良好的治疗效果。
Objective: To observe the therapeutic effect of tacrolimus on idiopathic membranous nephropathy. Methods: The clinical data of 50 patients treated in our hospital were analyzed retrospectively. In addition to the close observation of the clinical features of the patients, the experimental group and the control group were separated. The experimental group was treated with tacrolimus and the control group Cyclophosphamide and other drug treatment, analysis and comparison to observe the efficacy of each group. Results: The effective rates of the experimental group and the control group were 93.75% and 77.78% respectively. The treatment effect with tacrolimus had few side effects and was not easy to relapse after withdrawal. CONCLUSIONS: In patients with idiopathic membranous nephropathy, the treatment with tacrolimus is relatively good and can be significantly alleviated. There are few symptoms of ADR. In the course of treatment, tacrolimus should be treated correctly according to different physique characteristics of different patients Diagnosis, the right medicine, in order to achieve good therapeutic effect.