Expression of inhibin a and βA subunits in cultured human first trimester trophoblast tissue

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TWO protein hormones, which are dominantly produced by the gonads, are termed inhibin and aetivin since they can inhibit and stimulate the secretion of follicle-stimulating hormone (FSH) by anterior pituitary gland. They are also found in human placenta, and may regulate the placental hormonal secretion. However, control of inhibin subunit expression is not yet reported in human first trimester placenta. Here, using solution hybridization/nuclease protect assay, we determine expression of inhibin a and βA subunits in serum-free cultured trophoblast tissue from human first trimester placenta (6-9 week). TWO protein hormones, which are dominantly produced by the gonads, are termed inhibin and aetivin since they can inhibit and stimulate the secretion of follicle-stimulating hormone (FSH) by anterior pituitary gland. They are also found in human placenta, and may regulate the However, control of inhibin subunit expression is not yet reported in human first trimester placenta. Here, using solution hybridization / nuclease protect assay, we determine expression of inhibin a and βA subunits in serum-free cultured trophoblast tissue from human first trimester placenta (6-9 weeks).
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