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5. Asymmetric Synthesis of Anisodine

Asymmetric Synthesis of Anisodine

来源 :中国化学快报：英文版 | 被引量 : 0次 | 上传用户：xuyingheng

【摘 要】

：

Anisodine was synthesized from 3α-hydroxy-6β-acetyltropine in 11 steps. Laevorotary isomer of anisodine was prepared from the asymmetric dihydroxylation of co

【作 者】

：

Yan Fen WU Wen LUE Qiang LU We 

【机 构】

：

SchoolofPharmaceuticalSciences

【出 处】

：

中国化学快报：英文版

【发表日期】

：

2005年10期

【关键词】

：

托品碱 生物碱 不对称合成 药理活性 Anisodine  tropine alkaloid  total synthesis. 

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论文部分内容阅读

Anisodine was synthesized from 3α-hydroxy-6β-acetyltropine in 11 steps. Laevorotary isomer of anisodine was prepared from the asymmetric dihydroxylation of compound 10 via the osmium catalyzed process employing p-chlorobenzoyl dihydroquinidine as the chir

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