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本实验观察了温热、高渗液、化疗药物对人胃癌细胞株ＭＧＣ－８０３的细胞毒作用以及对细胞超微结构的影响。结果表明，随着温度的升高，癌细胞的克隆形成率逐步降低；单纯加温４３℃、３０分钟，不能杀死全部胃癌细胞；加温联合高渗液（７．５％ＮａＣｌ）和／或丝裂霉素Ｃ（ＭＭＣ）有明显的抗癌协同作用，三者联合应用，在４１℃、３０分钟即可杀死全部胃癌细胞；温热与５－氟脲嘧啶无抗癌协同作用。细胞的超微结构观察表明，温热作用的部位是在细胞质膜。本实验为持续性腹腔温热灌注治疗胃癌的腹膜种植（转移）提供了实验依据。
In this experiment, we observed the cytotoxic effects of warming, hyperosmotic solution, and chemotherapeutics on human gastric cancer cell line MGC-803 and its effect on cell ultrastructure. The results showed that with the increase of temperature, the colony formation rate of cancer cells gradually decreased; simply heating 43 °C, 30 minutes, can not kill all gastric cancer cells; warming combined with hypertonic solution (7.5% NaCl) and / Or mitomycin C (MMC) has significant anti-cancer synergistic effect. The combination of the three can kill all gastric cancer cells at 41° C. for 30 minutes. Warming and 5-fluorouracil have no synergistic effect on cancer. The ultrastructural observation of the cells showed that the site of warming is in the cytoplasmic membrane. This experiment provides experimental basis for the continuous abdominal warming perfusion treatment of peritoneal implantation (metastasis) of gastric cancer.