肠粘膜的一重要功能就是作为一个局部防御屏障阻止肠腔内正常所含有的细菌和内毒素扩散到远隔部位。但在特定环境下,细菌和内毒素能够穿越肠粘膜屏障播散到肠系膜淋巴结和全身脏器,这一过程称为细菌易位。越来越多的证据表明肠道屏障功能障碍和细菌易位在 An important function of the intestinal mucosa is to act as a partial defensive barrier that prevents the normal passage of bacteria and endotoxins from the intestine from spreading to distant sites. However, bacteria and endotoxins can diffuse across the intestinal mucosal barrier to mesenteric lymph nodes and systemic organs under certain circumstances, a process known as bacterial translocation. There is growing evidence that gut barrier dysfunction and bacterial translocations are present