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目的研究分析腹腔镜手术在子宫肌瘤中的疗效及对患者血清相关指标的影响。方法选取2011年1月至2012年12月本院收治的86例子宫肌瘤患者为研究对象,将其随机分为对照组(开腹手术组)43例和观察组(腹腔镜手术组)43例,然后将两组中不同肌瘤大小者的术中出血量、肛门排气时间、并发症发生率及手术前后的血清VEGF、IL-6、TNF-α及IL-10水平进行比较。结果观察组的术中出血量、肛门排气时间、并发症发生率方面均明显好于对照组,术后的血清IL-6、TNF-α及IL-10水平也显著性低于对照组,P<0.05,而两组的VEGF无显著性差异,P>0.05,但均显著低于术前,P<0.05。结论腹腔镜手术在子宫肌瘤中的疗效较好,且对患者血清相关指标的影响也较为明显。
Objective To study the effect of laparoscopic surgery in uterine fibroids and its influence on serum related indexes. Methods Totally 86 cases of uterine leiomyoma treated in our hospital from January 2011 to December 2012 were selected and randomly divided into control group (open surgery group) 43 cases and observation group (laparoscopic surgery group) 43 For example, we compared the intraoperative blood loss, the time of anal exhaust, the incidence of complications and the levels of serum VEGF, IL-6, TNF-α and IL-10 before and after surgery in two groups with different size of fibroids. Results The intraoperative blood loss, anal exhaust time and complication rate in the observation group were significantly better than those in the control group. The levels of IL-6, TNF-α and IL-10 in the observation group were also significantly lower than those in the control group P <0.05, but no significant difference between the two groups VEGF, P> 0.05, but were significantly lower than preoperative, P <0.05. Conclusion Laparoscopic surgery in uterine fibroids better curative effect, and the impact of serum-related indicators of patients is also more obvious.