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目的:分析江西南昌地区妊娠期高血压疾病(HDCP)与气候变化的相关关系。方法:收集HDCP孕妇896例,分析各季节型气候中HDCP的发病率及并发症发生率。结果:HDCP 896例占同期总住院的3.72%,冬季子痫前期发病高于夏季和春秋季(P<0.01);冬季HDCP合并孕妇严重并发症高于夏季和春秋季(P<0.05);妊娠高血压及子痫发病在冬季高于夏季和春秋季但差异无统计学意义(P>0.05);夏季围生儿不良结局高于春秋季和冬季型气候(P<0.05);HDCP与平均温度呈显著负相关(P<0.01),与大气压呈正相关(P<0.05),孕妇合并严重并发症与平均温度呈显著负相关(P<0.01),与大气压呈显著正相关(P<0.01);未发现湿度、降雨量与HDCP发病之间的相关性(P>0.05),HDCP围生儿并发症发生率与温度、湿度、大气压、降雨量无显著相关(P>0.05)。结论:HDCP发病可能与气候相关,平均温度、大气压与HDCP发病及孕妇严重并发症发生相关,其中关联需要进一步研究。
Objective: To analyze the relationship between HDCP and climate change in Nanchang, Jiangxi Province. Methods: 896 HDCP pregnant women were collected to analyze the incidence of HDCP and the incidence of complications in each seasonal climate. Results: 896 cases of HDCP accounted for 3.72% of the total hospitalization in the same period, and the incidence of winter preeclampsia was higher than that of summer and spring (P <0.01). The incidence of severe HDCP complicated with pregnant women in winter was higher than that of summer and spring (P <0.05) The incidence of hypertension and eclampsia was higher in summer than in summer and spring and autumn (P> 0.05). The adverse outcomes in summer were higher than those in spring, autumn and winter (P <0.05) (P <0.01), and was positively correlated with the atmospheric pressure (P <0.05). There was a significant negative correlation between the serious complications of pregnant women and the average temperature (P <0.01) and the positive correlation with the atmospheric pressure (P <0.01). The correlation between the incidence of HDCP and the incidence of HDCP was not found (P> 0.05). The incidence of perinatal complications of HDCP was not significantly correlated with temperature, humidity, barometric pressure and rainfall (P> 0.05). Conclusion: The incidence of HDCP may be related to the climate. The mean temperature and atmospheric pressure are related to the incidence of HDCP and the serious complications of pregnant women. The association needs further study.