【摘 要】
：
目的:研究荔枝核提取液对甲1型流感病毒鼠肺适应株的影响.方法:用病毒滴鼻感染小鼠建立病毒感染小鼠模型,观察肺指数、病毒致小鼠死亡率.停药后处死小鼠,取各组小鼠肺组织光
【机 构】
：
广州中医药大学,广东,广州,510405
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目的:研究荔枝核提取液对甲1型流感病毒鼠肺适应株的影响.方法:用病毒滴鼻感染小鼠建立病毒感染小鼠模型,观察肺指数、病毒致小鼠死亡率.停药后处死小鼠,取各组小鼠肺组织光镜和电镜观察.结果:荔枝核高、低剂量组对小鼠流感病毒性肺炎均有抑制作用,对流感病毒感染小鼠有明显的死亡保护作用.在光镜与电镜观察下,正常对照组小鼠肺组织形态学未发生改变,病毒模型组肺组织明显出现克血、变性、白细胞浸润等现象,治疗组肺组织充血等现象明显轻于模型组.结论:荔枝核提取液在小鼠体内具有抗FM1流感病毒的作用.
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