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目的评价玻璃体腔注射曲安奈德(TA)联合黄斑部格栅样光凝治疗弥漫性糖尿病性黄斑水肿的治疗效果。方法对56眼糖尿病性弥漫性黄斑水肿(DME)患者随机分为两组,单纯黄斑部格栅样光凝组和联合治疗组,每组28眼。对两组治疗前及治疗后3、6个月最佳矫正视力、黄斑水肿的变化分析。结果两组差异有统计学意义。结论 TA玻璃体腔注射联合激光光凝治疗DME较单纯黄斑部格栅样光凝治疗能更好地提高视力,减轻黄斑水肿。
Objective To evaluate the therapeutic effect of intravitreal triamcinolone acetonide (TA) combined with macular grid photocoagulation in the treatment of diffuse diabetic macular edema. Methods 56 patients with diabetic macular edema (DME) were randomly divided into two groups, simple macular grid-like photocoagulation group and combination therapy group, 28 eyes in each group. Changes of the best corrected visual acuity and macular edema in the two groups before treatment and 3 and 6 months after treatment were analyzed. Results The difference between the two groups was statistically significant. Conclusions TA intravitreal injection combined with laser photocoagulation for the treatment of DME shows better visual acuity and lesser macular edema than pure macular grid-like photocoagulation.