古典的NSAIA类药——水杨酸盐应用于临床的文献记载迄今已有百余年历史;阿斯匹林(乙酰水杨酸)于1899年已见用于眼科临床;Harold Gifford首先提出应用水杨酸盐治疗色素膜炎病例。开始应用大剂量,然后降低用量至耐受水平。最早的实验通过马血清引起的动物色素膜炎模型,用阿斯匹林有效;5%水杨酸盐治疗可使炎症反应的产生显著减轻。本世纪40年代后期,由于甾体皮质激素治疗 The classic NSAIA drug salicylate has been used clinically for over a hundred years; aspirin (acetylsalicylic acid) has been used in ophthalmology in 1899; Harold Gifford first proposed the use of Salicylate treatment of pigmented meningitis cases. Start applying large doses, then reduce dosage to tolerate levels. In the earliest experiments, the animal model of pigmentation caused by horse serum was treated with aspirin; 5% salicylate significantly reduced the inflammatory response. The late 1940s, due to steroid treatment