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目的 :了解表皮葡萄球菌 (以下简称表葡菌 )在医院感染中的状况。方法 :对 1 994年 1月～1 998年 1 2月本院 2 5 6例表葡菌感染引起的医院感染病例的诱发因素、侵袭部位、预后情况以及表葡菌对抗菌药物的敏感情况进行分析。结果 :2 5 6例表葡菌感染者 ,曾经历过 5 1 9次侵袭性操作及1 0 3次大小手术。感染部位分布以下呼吸道居首位 (占 5 6 .5 5 % ) ,其次为血液、上呼吸道、手术伤口及泌尿道等。表皮葡萄球菌的耐药率多数在 40 %以上 ,敏感抗生素有万古霉素、丁胺卡那、头孢哌酮钠 /舒巴坦钠、头孢三嗪、亚胺硫霉素 -西拉司丁钠等。结论 :除了恶性肿瘤、血液病、颅脑疾患、重大手术以及各种慢性疾患因免疫力低下为其诱发因素外 ,各种侵袭性操作、置管、穿刺、介入疗法等对其感染具有特别意义。
Objective: To understand the situation of Staphylococcus epidermidis (hereinafter referred to as Staphylococcus epidermidis) in hospital infection. Methods: The etiological factors, invasion sites and prognosis of nosocomial infections caused by 25 S. aureus infection in our hospital from January 1994 to January 1998 were analyzed retrospectively and the susceptibility of S. epidermidis to antimicrobial agents analysis. Results: Twenty-five (6) cases of Staphylococcus aureus infection had undergone 5 1 9 invasive procedures and 103 size surgeries. Infected parts of the distribution of the following respiratory tract first place (accounting for 56.55%), followed by blood, upper respiratory tract, surgical wounds and urinary tract. Staphylococcus epidermidis resistance rates mostly in more than 40%, sensitive antibiotics vancomycin, amikacin, cefoperazone sodium / sulbactam sodium, ceftriaxone, imimuosin - cilastatin sodium. CONCLUSION: In addition to malignant tumors, blood diseases, craniocerebral disorders, major surgeries and various chronic diseases due to low immunity, various invasive procedures, catheterization, puncture and interventional therapy are of particular significance to their infection .