论文部分内容阅读
目的探讨青春期卵巢肿瘤的临床病理特点。方法回顾性分析1999年1月至2009年12月我院收治的98例10～20岁青春期卵巢肿瘤患者的临床资料。结果青春期卵巢肿瘤发病率为5.8%,临床表现主要为腹痛、腹胀、下腹部肿物、月经异常,部分为体检或自己触诊发现。98例均行手术治疗,病理结果为生殖细胞肿瘤56例,上皮性肿瘤36例,性索间质肿瘤4例,混合型生殖细胞肿瘤2例。治疗首选保守性手术,良性肿瘤90例,行卵巢肿瘤剔除术68例,患侧附件切除术22例;8例恶性肿瘤6,例行患侧附件切除术、大网膜切除术;2例行卵巢肿瘤剔除术。恶性肿瘤患者术后辅以化疗。随访至今,除1例内胚窦瘤患者死亡外,其余患者至今均生存良好。结论青春期卵巢肿瘤临床表现、病理类型及其治疗原则均与成年女性存在差异。建议对青春期少年开展普查性体检,必要时行B超检查,治疗应兼顾治愈肿瘤和保留生育功能。
Objective To investigate the clinicopathological features of adolescent ovarian tumors. Methods The clinical data of 98 cases of adolescent ovarian tumors between the ages of 10 and 20 admitted to our hospital from January 1999 to December 2009 were analyzed retrospectively. Results The incidence of adolescent ovarian cancer was 5.8%. The main clinical manifestations were abdominal pain, abdominal distension, abdominal mass and abnormal menstruation. Some of them were diagnosed by physical examination or palpation. Surgical treatment of 98 cases were performed. The pathological results were 56 cases of germ cell tumors, 36 cases of epithelial tumors, 4 cases of sex cord stromal tumors and 2 cases of mixed germ cell tumors. The treatment of choice for conservative surgery, benign tumors in 90 cases, ovarian tumor resection in 68 cases, ipsilateral adjuvant resection in 22 cases; 8 cases of malignant tumors 6, routine ipsilateral adjunctive resection, omental resection; 2 routine Ovarian tumor excision. Patients with malignant tumors were treated with chemotherapy. Up to now, except one case of endodermal sinus tumor patients died, the other patients have so far survived. Conclusion The clinical manifestations, pathological types and treatment principles of adolescent ovarian tumors are different from those of adult women. It is recommended to carry out general physical examination for adolescent boys, if necessary, B-ultrasound, treatment should take into account the tumor and retain reproductive function.