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近交系动物是生物医学研究的重要工具。它在遗传上的同和性(homozygosity)使其具有同卵孪生子的特性。自从第一株近交系小鼠DBA有成以来,人们就开始利用同系异体皮肤移植方法来鉴定小鼠的纯度。近年来,鉴定近交系小鼠的方法越来越多。但是,没有一个方法可以单独地取代异性皮肤移植法。国内常常采用背部皮片移植法,国外采用尾部皮片移植法。1960年,贝立博士首次介绍了这种方法。本文着重介绍尾部皮片移植的方法,并与背部皮肤移植法进行比较。本法也适用于大鼠鉴定。材料与方法 (一)材料 (1)KK小鼠,1949年由日本的Kasukabe小组育成,现已90代以上。1983年本中心引进,现已繁殖7代。
Inbred animals are an important tool in biomedical research. It is genetically homozygosity making it an identical twins. Since the first inbred mouse DBA has been established, people began to use the allograft skin graft method to identify the purity of mice. In recent years, there have been more and more methods for identifying inbred mice. However, there is no single alternative to heterosexual skin transplantation. Domestic back skin graft method is often used, the use of tail skin graft method abroad. In 1960, Dr. Belli introduced it for the first time. This article focuses on the tail skin graft method, and compared with the back skin graft method. This law is also applicable to rat identification. Materials and Methods (1) Materials (1) KK mice, bred by the Japanese group Kasukabe in 1949, are now over 90 generations. The introduction of the Center in 1983, has now been breeding 7 generations.