氯苯类化合物是化工生产中的重要原料,是一类在环境中广泛分布的有机物,对水生物产生一定的毒性。该类化合物对水生物的毒性构效关系的研究对保护水环境有着重要意义,因此引起了科学界的重视。Ｋａｉｓｅｒ等[1]曾测定了氯苯化合物对虹鳟鱼的半致死量。目前的观点认为:氯苯化合 Chlorobenzenes are important raw materials in chemical production. They are a type of organic substances widely distributed in the environment and have some toxicity to aquatic organisms. The study on the toxicological structure-activity relationship of these compounds to aquatic organisms is of great significance for the protection of the aquatic environment, and therefore has drawn the attention of the scientific community. Kaiser et al [1] have measured the LD50 of chlorobenzene compounds on rainbow trout. The current view that: chlorobenzene