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1966年有人再次发现吞噬性白细胞(即中性粒细胞和单核细胞)可将可溶性黄色的四唑氮兰(NBT)还原为不溶解的兰黑色甲?。1968年Park等以较简单的组织化学方法,对少数健康人及细菌、病毒感染与非感染性疾病的儿童作试验,认为自发的NBT试验可用来鉴别细菌与非细菌性疾病。以后国外积累了许多资料,国内也开展了这方面的研究。还有人发现少数红细胞葡萄糖-6-磷酸脱氢酶(G-6-PD)缺乏者的吞噬细胞有异常,NBT还原率低。为配合临床需要,我们
In 1966, it was once again found that phagocytic leukocytes (ie, neutrophils and monocytes) reduced soluble yellow tetrazolium nitrogen (NBT) to insoluble blue black. In 1968 Park and other simpler histochemical methods for a small number of healthy people and bacteria, viral infections and non-infectious diseases in children, that the spontaneous NBT test can be used to identify bacterial and non-bacterial diseases. Since then accumulated a lot of information abroad, China has also carried out research in this area. It was also found that a small number of red blood cells in the absence of glucose-6-phosphate dehydrogenase (G-6-PD) phagocytes are abnormal, NBT reduction rate is low. To meet the clinical needs, we