论文部分内容阅读
以环糊精及其衍生物作为毛细管电泳手性分离的添加剂，采用正极进样，对酸性药物萘普生对映体的分离进行研究，结果表明该途径能在较短的时间内使对映体达到基线分离。还研究了缓冲体系ｐＨ值对萘普生对映体分离的影响，结果表明，ｐＨ５．５时分离效果最佳，且耗时最短。对ＣＥ定量能力（线性，精度）进行了考察，获得满意的结果，线性相关系数为０．９９８，ＲＳＤ低于４．４％
Cyclodextrin and its derivatives were used as additives for the chiral separation of capillary electrophoresis. The separation of the enantiomers of the naproxen acid was studied by positive sample injection. The results showed that this route can make the enantiomers of enantiomers in a relatively short time Body to baseline separation. The effect of buffer pH on the enantiomer separation of naproxen was also studied. The results showed that pH5.5 had the best separation efficiency and the shortest time. CE quantitative ability (linearity, precision) were investigated to obtain satisfactory results, the linear correlation coefficient of 0.998, RSD less than 4.4%