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在结直肠手术中伤口感染仍然是有待解决的问题.本文旨在比较作选择性结直肠手术后感染性并发症方面,术前短期口服新霉素、红霉素和手术前后全身应用灭滴灵、庆大霉素两种方法的预防作用.本研究系前瞻性、随机化试验,对象限于择期性结直肠手术,术中均切开肠道者.凡术前48小时内用过抗生素者,病人合并有感染需用抗生素治疗者、有结肠炎性疾病者及全身情况差者和妊娠妇女均予剔除.在1980.8～1982.7月期间,适合于本研究者共93例,经随机化抽签将病人分为二组.第一组45例、第二组48例,两组病人年龄、性别、临床诊断及手术持续时间、手术方式大致相同.两组病人均于手术前20小时口服生理盐水及10%甘露醇液各1升作肠道机械性灌洗,第一组病人于手术前22小时(接受甘露
Wound infection in colorectal surgery is still a problem to be solved.This paper aims to compare infectious complications after selective colorectal surgery, short-term oral administration of neomycin, erythromycin and preoperative and postoperative systemic metronidazole , Gentamicin two methods of preventive effect.This study was prospective, randomized trials, the object is limited to elective colorectal surgery, intraoperative incision of the intestine.All those who used antibiotics within 48 hours before surgery, Patients with infection need antibiotic treatment, those with colitis disease and poor general condition and pregnant women were removed in the period 1980.8 ~ 1982.7 months, suitable for a total of 93 patients in this study, the randomized draw patients Divided into two groups.The first group of 45 cases, the second group of 48 cases, two groups of patients age, gender, clinical diagnosis and duration of surgery, the same surgical approach.The two groups were 20 hours before surgery, oral saline and 10 1% of mannitol solution for intestinal mechanical lavage, the first group of patients 22 hours before surgery (to accept mannitol