Dear Editor,rnWe present here a rare case of primary malignant lymphoma of the glans penis that was detected in a 72-year-old man.Additionally,we have reviewed the literature for reports of primary malignant lymphoma of the penis.This is most likely the forty-ninth case of primary malignant lymphoma of the penis reported in the medical literature.Lymphomas typically originate from the lymph nodes and lymph tissues;however,the tonsils,spleen and bone marrow are also vulnerable sites.Due to the presence of lymph nodes and lymph tissue throughout the human body,primary malignant lymphomas of glans penis occur rarely.The diagnosis of this rare lymphoma may be difficult and delayed without specific symptoms,and treatment modalities are controversial because of the limited number of patients.