猪生殖道与呼吸道综合征病毒(PRRSV)在全世界养猪场中广为流行,并且是经济损失和动物罹难的主要原因。PRRSV的快速遗传变异对于现行疫苗提供抗新出现的毒株保护作用而言是很困难的。作者近来证实一种新型肽纳米纤维水凝胶配方制剂(H9e)对于灭活的H1N1疫苗而言可作为有效的佐剂而起作用。因此,这项研究的目的是评价H9e作为一种用于PRRSV改良活病毒疫苗(MLV) Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) is widespread in pig farms throughout the world and is a major cause of economic loss and animal fatalities. Rapid genetic variation of PRRSV is difficult for current vaccines to provide protection against emerging strains. The authors recently demonstrated that a novel peptide nanofiber hydrogel formulation (H9e) can act as a potent adjuvant for inactivated H1N1 vaccines. Therefore, the purpose of this study was to evaluate H9e as a vaccine for PRRSV-modified live virus vaccine (MLV)