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目的:探讨顽固性老年高血压病的联合药物治疗方法与效果。方法:选择顽固性老年高血压病100例,分为治疗组与对照组各50例,在常规对症治疗基础上,对照组单独采用依那普利治疗,治疗组采用缬沙坦联合依那普利治疗。结果:经过治疗后,治疗组50例总有效率为91.7%;对照组50例总有效率为70.0%,两组相比有统计学差异(P<0.05)。两组治疗前的SBP、DBP比较无显著差异(P>0.05);治疗后两组SBP、DBP显著降低(P<0.05),但治疗组的下降幅度明显高于对照组(P<0.05)。结论:顽固性老年高血压病应积极采用药物联合治疗,以提高治疗效果,降低血压水平。
Objective: To investigate the combined drug therapy and effect of refractory senile hypertension. Methods: 100 cases of refractory senile hypertension were divided into treatment group and control group of 50 cases. On the basis of routine symptomatic treatment, the control group was treated with enalapril alone. The treatment group received valsartan combined with enalapril Lee treatment. Results: After treatment, the total effective rate of 50 cases in the treatment group was 91.7%. The total effective rate in the control group was 70.0%. There was significant difference between the two groups (P <0.05). There was no significant difference in SBP and DBP between the two groups before treatment (P> 0.05). The SBP and DBP in the two groups were significantly decreased (P <0.05) after treatment, but the decrease in the treatment group was significantly higher than that in the control group (P <0.05). Conclusion: refractory senile hypertension should be actively used drug combination therapy to improve the therapeutic effect and lower blood pressure levels.