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为了更好地了解各期系统性红斑狼疮(SLE)病人肾损害程度及治疗效果,我们做了各期SLE病人的尿液和血液β_2-MG的含量测定,同时做了尿蛋白定性作为对照,现报告如下。1 材料与方法 1.1 材料 标本来自本院门诊和住院的23例病人,其中男性4例,女性19例,年龄15～62岁,诊断依据我国SLE诊断标准(1982年修订),其中临床表现不明显而实验室检查足以确诊的SLE(暂称亚临床型)3例,活动期(病人出现发热、关节痛、皮疹、主要脏器损害等急性症状)服用大剂量的类固醇激素13例,稳定期(是指病人在用少量激素或停药较长时间内,病情稳定、症状消失者)7例。另外正常对照30例(标本来自排除各类相关疾病的健康查体者),年龄21～49岁。
In order to better understand the degree of renal damage and treatment effect in patients with systemic lupus erythematosus (SLE) in various stages, we have done the determination of urinary and blood β_2-MG levels in patients with SLE at different stages, meanwhile made urine protein qualitative as a control, The report is as follows. 1 Materials and Methods 1.1 Materials Specimens from our hospital outpatient and hospitalized 23 patients, including 4 males and 19 females, aged 15 to 62 years old, the diagnosis based on SLE diagnostic criteria (revised in 1982), in which the clinical manifestations were not obvious The laboratory tests were sufficient to confirm the SLE (tentatively called subclinical) in 3 cases, the active phase (patients with fever, joint pain, rash, major organ damage and other acute symptoms) taking high-dose steroid hormone in 13 cases, stable Refers to the patient with a small amount of hormone or withdrawal for a long time, stable condition, the symptoms disappeared) 7 cases. Another normal control in 30 cases (specimens from all kinds of related diseases to exclude the physical examination), aged 21 to 49 years old.