寻常性天疱疮属于自家免疫性疾患,口腔粘膜是最好发的部位,据Laskaris等统计,55—65%以上病例原发于口腔粘膜,且病变可持续几周、几月甚至几年而仅局限于口腔粘膜。Rosenberg等(1976)曾报导过一例病变局限在口腔粘膜达13年之久。自Beutnet和Jordon(1964)用间接免疫荧光实验(Indirect immunofluorescence,IIF)在患者血清中发现特异性抗体以 Pemphigus vulgaris belong to the autoimmune disease, oral mucosa is the best hair site, according to Laskaris and other statistics, 55-65% of the cases were primary in the oral mucosa, and the lesions can last for weeks, months or even years Only limited to oral mucosa. Rosenberg et al. (1976) reported that one of the lesions was localized to the oral mucosa for 13 years. Specific antibodies were found in the sera of patients by Indirect immunofluorescence (IIF) from Beutnet and Jordon (1964)