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报告四例我们所遇到的幼年性粒层细胞瘤。该瘤系粒层细胞瘤的一种特殊类型,临床经过一般为良性,多发生于青春期前及青春期女性,组织病理学特征为滤泡结构不成熟,滤泡内有粘液性分泌物,罕见Call-Exner小体,细胞核深染,可有中度异型性,罕见核沟,常见核分裂,且黄素化粒层细胞甚多。因此,与一般成人粒层细胞瘤形态上颇不相同,每易造成误诊,甚至误诊为恶性肿瘤,招致对年青病人的过度治疗。幼年性粒层细胞瘤这一名称系Scully(1977)提出,至今国外已报道一百多例,国内尚未见报告。
Four cases of juvenile pleomorphocytoma we encountered were reported. The tumor is a special type of granulocytoma, usually clinically benign, occurs in pre-adolescent women and adolescents, histopathological features of immature follicular structure, follicular mucus secretions, a rare Call -Exner bodies, deep-stained nuclei, may have moderate atypia, rare nuclear ditch, common mitotic, and luteinized granulosa cells. Therefore, with the general adult granulosa cell tumor morphology is quite different, each easily lead to misdiagnosis, or even misdiagnosed as malignant tumors, leading to over-treatment of young patients. The name of juvenile stratum cell tumor Scully (1977) proposed that so far more than 100 cases have been reported abroad, the country has not yet reported.