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本院5年来手术治疗的168例直肠癌病人中,有20例(11.9%)第一次手术前活检不能明确诊断.对其中17例患者的活检组织石蜡标本进行常规病理和图象细胞分析(ICM)检测.ICM检查有53%(9/17)为异倍体,与常规病理比较,差异有统计学意义.17例患者的标本中,11例为不典型增生,5例仅有慢性炎.通过ICM检测,不典型增生中有8例为异倍体而慢性炎全部为二倍体.根据上述结果,作者认为ICM可以作为常规病理检查的补充,提高结肠良恶性病变的鉴别力.
Of the 168 patients with rectal cancer who had been treated surgically for 5 years in this hospital, 20 (11.9%) had no prior diagnosis before the first preoperative biopsy. Routine pathology and image cytometry analysis was performed on paraffin-embedded biopsy specimens from 17 patients. ICM) detection. 53% (9/17) of the ICM examination was aneuploid, and the difference was statistically significant compared to the conventional pathology. Of the 17 patients, 11 were dysplasia and 5 had only chronic inflammation. By ICM detection, 8 cases of dysplasia were aneuploid and chronic inflammation were all diploid. According to the above results, the author believes that ICM can be used as a supplement to routine pathological examination to improve the differentiation of benign and malignant lesions of the colon.