口服药联合NPH治疗2型糖尿病疗效观察

来源 :实用糖尿病杂志 | 被引量 : 0次 | 上传用户:gwbn9
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选择26例采用饮食控制及口服降糖药物治疗血糖控制不满意的2型糖尿病病例,于晚睡前注射1次中效胰岛素(NPH)治疗,分别于治疗前及治疗后观察空腹血糖(FBG)及糖化血红蛋白(HbA1c)的变化。结果表明加用NPH治疗后FBG、HbA1c均较前有明显下降(P<0.05),且低血糖发生少。提示口服降糖药物联合睡前注射NPH方案具有降糖作用佳,安全性良好的特点。 Twenty-six patients with type 2 diabetes who were not satisfied with glycemic control by diet control and oral hypoglycemic agents were enrolled in this study. One dose of NPH was injected before going to bed at night. Fasting plasma glucose (FBG) And glycosylated hemoglobin (HbA1c) changes. The results showed that after treatment with NPH FBG, HbA1c were significantly lower than before (P <0.05), and less hypoglycemia. Prompt oral hypoglycemic agents combined with NPH bedtime injection has good hypoglycemic effect, good safety features.
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