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目的分析胰岛素抵抗与非胰岛素抵抗多囊卵巢综合征的临床治疗效果。方法 108例多囊卵巢综合征患者为研究对象,其中56例为胰岛素抵抗患者为A组,52例为非胰岛素抵抗患者为B组。两组患者均给予常规治疗,A组在此基础上给予二甲双胍治疗,观察分析两组患者的临床治疗效果。结果 A组患者卵泡激素(FSH)、黄体生成素(LH)、雌二醇(E2)、睾丸酮(T)等血清性激素各项指标均明显小于B组,差异具有统计学意义(P<0.05)。B组患者治疗后巢内小卵泡数量、排卵率变化程度均大于A组(P<0.05)。结论胰岛素抵抗多囊卵巢综合征患者相比于非胰岛素抵抗患者的临床治疗,需要对胰岛素抵抗状态进行调节,才能有效控制病情,降低并发症的发生率。
Objective To analyze the clinical effect of insulin resistance and non-insulin resistance polycystic ovary syndrome. Methods A total of 108 patients with polycystic ovary syndrome were enrolled in this study. Among them, 56 were insulin resistant patients, group A, and 52 were non-insulin resistant patients. Two groups of patients were given conventional treatment, A group was given metformin on this basis, the clinical efficacy of the two groups were observed and analyzed. Results The serum levels of FSH, LH, E2 and T in group A were significantly lower than those in group B (P <0.05) . After treatment, the number of small follicles in the nests and the ovulation rate of the patients in group B were all higher than those in group A (P <0.05). Conclusion Insulin resistance in patients with PCOS compared with non-insulin resistance in patients with clinical treatment, need to adjust the state of insulin resistance in order to effectively control the disease and reduce the incidence of complications.