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目的了解抗菌药物应用现状和存在的问题,探讨抗菌药物的合理应用。方法从佳木斯大学附属第一医院住院药房管理系统中随机抽取2010年住院病历共780份,进行回顾性分析。结果使用抗菌药物6大类20多个品种,抗菌药物使用率为62.8%,用药频率最高的抗菌药物为头孢菌素类占55.6%,其次为青霉素类。不合理应用主要表现为无指征用药(40.3%)、选药起点较高(38.3%)、疗程不合理(27.8%)等。结论佳木斯大学附属第一医院抗菌药物使用基本合理,但仍需进一步加强管理,保证临床用药安全、经济、有效。
Objective To understand the current status and existing problems of antimicrobial agents and to explore the rational application of antimicrobial agents. Methods A total of 780 in-patient records of 2010 were randomly selected from the inpatient pharmacy management system of the First Affiliated Hospital of Jiamusi University for retrospective analysis. The results of the use of antibacterial drugs in more than 20 varieties of six major categories, the use of antimicrobial drugs was 62.8%, the highest frequency of antibacterial drugs for cephalosporins accounted for 55.6%, followed by penicillins. Unreasonable applications mainly showed no indication for medication (40.3%), high starting point for medicine (38.3%), unreasonable treatment (27.8%) and so on. Conclusion The use of antimicrobial agents in Jiatusi First Affiliated Hospital was basically reasonable, but management was still needed to be further strengthened to ensure the safety, economy and effectiveness of clinical medication.