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目的：探讨适合基层Ｈｐ阳性的消化性溃疡的治疗方法。方法：４５例符合条件的病人随机分成三个治疗组：（１）Ｒ组单用雷尼替丁，（２）ＡＭ组羟氨苄青霉素与甲硝唑，（３）ＲＡＭ组雷尼替丁、羟氨苄青霉素与甲硝唑。三组疗程均为２周，疗程结束后６周复查胃镜、尿素酶试验、病理切片染色查Ｈｐ。结果：三组溃疡愈合无显著性差异。但在ＨＰ根除率方面，ＡＭ组（８７．５％）ＲＡＭ组（８５．７％）均优于Ｒ组（２６．６７％），且无明显副作用。结论：单用雷尼替丁对ＨＰ根除无明显作用，合用两种抗生素有较理想的溃疡愈合率和ＨＰ根除率。适合我国基层治疗ＨＰ阳性的消化性溃疡
Objective: To explore the treatment of peptic ulcer suitable for primary Hp positive. METHODS: Forty-five eligible patients were randomized into three treatment groups: (1) ranitidine alone in group R, (2) amoxicillin and metronidazole in AM group, (3) ranitidine in RAM group, Amoxicillin and metronidazole. Three courses of treatment were 2 weeks, 6 weeks after the end of the course of examination gastroscope, urease test, histological staining Hp. Results: The three groups of ulcer healing no significant difference. However, in terms of HP eradication rate, AM group (87.5%) RAM group (85.7%) was superior to R group (26.67%) with no obvious side effects. Conclusion: Ranitidine alone had no significant effect on the eradication of HP, and the combination of two antibiotics had better ulcer healing rate and HP eradication rate. For our primary treatment of HP-positive peptic ulcer