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本文报道乙胺碘呋酮对20例持续性房颤的复律效果。20例房颤持续时间,2例为6天和11天,18例在1.5～96月。乙胺碘呋酮日量为0.3～0.8,用药时间一般不超过一个月。个别长达3个月。20例中,2例转复失败,18例于服药后心律转复为窦性。18例有效病例中,13例于心律转复后经1～22个月随访,在隔日或每日0.1～0.2维持量支持下,一直保持窦性心律。3例分别在停药后72天、90天和9月余(1例心肌炎患者)心律失常均未复发。本组1例风湿性心脏病患者在复律过程中发生心室扑动,后经心肺复苏脱险。提示尽管本药是相对安全的,但对剂量较大疗程较长的患者必须严密观察 Q-T 间期动态变化,以防发生意外。
This article reports the effect of amiodarone on cardioversion in 20 patients with persistent atrial fibrillation. 20 cases of atrial fibrillation duration, 2 cases of 6 days and 11 days, 18 cases in 1.5 to 96 months. Amiodarone day 0.3 to 0.8, medication time is generally not more than one month. Individual up to 3 months. Of the 20 cases, 2 failed to recover, and 18 received sinus rhythm after taking the medication. Of the 18 valid cases, 13 were followed up from 1 to 22 months after cardioversion, and sinus rhythm was maintained on the next day or daily maintenance of 0.1 to 0.2. No recurrence of cardiac arrhythmia occurred in 72 cases, 90 days and 9 months (1 case of myocarditis) in 3 cases after stopping drug treatment. The group of patients with rheumatic heart disease during cardioversion occurred ventricular flutter, after cardiopulmonary resuscitation risk. Tip Although the drug is relatively safe, but for longer doses of larger doses of patients must closely observe the Q-T dynamic changes in time to prevent accidents.