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为了评价介入性肾动脉栓塞化疗(TACE)结合手术治疗肾母细胞瘤的有效性和可行性,回顾性分析我院收治的88例肾母细胞瘤患者的临床资料,分别采用术前行TACE治疗(研究组48例)和单纯手术治疗(对照组40例),评价肾母细胞瘤术前TACE的优缺点。TACE结合对照组在行TACE后44例患者的肿块明显缩小,平均缩小39.2%,且在手术切除肿瘤的包膜完整性(研究组40/48,对照组16/40)、肿瘤完全切除率(研究组48/48,对照组20/40)和术中出血量〔研究组(115.2±61.7)mL,对照组(220.8±105.3)mL〕方面,明显优于对照组。初步研究结果提示,肾母细胞瘤术前介入治疗能有效提高肿瘤的完整切除率,降低手术风险和复发的概率,有较高的临床应用价值。
In order to evaluate the effectiveness and feasibility of interventional renal artery thrombosis (TACE) combined with surgical treatment of Wilms’ tumor, we retrospectively analyzed the clinical data of 88 patients with nephroblastoma treated in our hospital. TACE was performed preoperatively (48 in study group) and simple surgery (40 in control group), to evaluate the advantages and disadvantages of preoperative TACE in nephroblastoma. TACE combined with control group 44 patients after TACE significantly reduced the mass, an average reduction of 39.2%, and in the surgical removal of the tumor capsule integrity (study group 40/48, control group 16/40), complete tumor resection rate 48/48 in the study group and 20/40 in the control group) and blood loss in the study group (115.2 ± 61.7 mL in the study group and 220.8 ± 105.3 mL in the control group). Preliminary results suggest that preoperative interventional treatment of nephroblastoma can effectively improve the complete resection rate of tumor, reduce the risk of surgery and the probability of recurrence, and has a high clinical value.