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急性一氧化碳中毒(ACOP)急救治疗主要包括氧疗、用药、并发症对症治疗与特殊患者的救治四个组成部分。高压氧疗是一线疗法,疗效肯定。治疗药物主要包括神经保护药物、自由基清除剂、促醒药醒脑静以及纳洛酮、糖皮质激素、脑细胞赋活剂、胞二磷胆碱、神经营养药B族维生素、抗血小板、扩血管药物等。血气分析是进行病情监护的重要方法,连续监测非常关键,仪器设备能够实时动态评价患者血气状态,用于分析高压氧疗的疗效。其他常用的指标还包括乳酸与乳酸清除率、血CK-BB动态变化等,影像学在ACOP迟发性脑病的预测以及诊断中也有较高的价值。ACOP疗效预测以及迟发性脑病的预测比较困难,不利于预防性治疗开展,尚需进一步的研究。
Acute carbon monoxide poisoning (ACOP) first aid treatment include oxygen therapy, medication, complications of symptomatic treatment and treatment of special patients with four components. Hyperbaric oxygen therapy is first-line therapy, efficacy is positive. Therapeutic drugs include neuroprotective drugs, free radical scavengers, arousal drugs and brain naloxone, glucocorticoids, brain cell activators, citicoline, neurotrophic agents B vitamins, anti-platelet, Vasodilator drugs. Blood gas analysis is an important method of patient monitoring. Continuous monitoring is crucial. Instruments and equipment can dynamically evaluate the blood gas status of patients in real time and analyze the effect of hyperbaric oxygen therapy. Other commonly used indicators include lactic acid and lactic acid clearance, the dynamic changes of blood CK-BB, imaging studies in the prediction and diagnosis of ACOP delayed encephalopathy also have high value. ACOP curative effect prediction and prediction of delayed encephalopathy is more difficult, which is not conducive to the implementation of preventive treatment, further study is needed.