论文部分内容阅读
[目的]研究微米大黄炭对乙酸胃溃疡(GU)大鼠胃黏膜病理组织的影响。[方法]用冰醋酸制备大鼠慢性GU模型,随机分为正常组、模型对照组、微米大黄炭组、雷尼替丁组4组,分别以0.85%氯化钠、微米大黄炭和雷尼替丁灌胃,观察GU大鼠黏膜肌层缺损宽度和再生黏膜厚度。[结果]微米大黄炭组和雷尼替丁组再生黏膜厚度高于正常组(P<0.05),黏膜肌层缺损宽度低于正常组(P<0.01),而微米大黄炭组与雷尼替丁组比较差异无统计学意义。[结论]微米大黄炭促进黏膜再生,降低黏膜肌层缺损宽度,具有保护胃黏膜作用。
[Objective] To study the effect of micron rhubarb charcoal on gastric mucosal pathological tissue in acetic acid gastric ulcer (GU) rats. [Methods] The rat model of chronic GU was prepared with glacial acetic acid and randomly divided into normal group, model control group, micron rhubarb charcoal group and ranitidine group 4 groups with 0.85% sodium chloride, micron rhubarb charcoal and Renie respectively. Tedding gavage to observe the width of mucous muscle defect and the thickness of regenerated mucosa in GU rats. [Results] The thickness of regenerated mucosa in micron rhubarb charcoal group and ranitidine group was higher than that in normal group (P<0.05), and the defect width of mucosal muscularis was lower than that in normal group (P<0.01), while micron rhubarb charcoal group and ranitidine group. There was no statistically significant difference in the D group. [Conclusion] Micron rhubarb charcoal can promote the regeneration of mucosa, reduce the width of mucosal muscularis defect, and protect gastric mucosa.